Apathy in Parkinson Disease TMS Study

Description

Participants will be asked to come for 3 study visits.

During visit 1, after being informed about the study and potential risks, all patients giving written informed consent will undergo a brief cognitive assessment, a movement examination, and answer questionnaires. Additionally, the individual motor threshold will be determined for each participant. Visit 1 will take 2-3 hours.

Visits 2 and 3 will involve:

* completing questionnaires,
* performing a task where fictitious rewards can be earned by squeezing a dynamometer,
* recording brain activity with an electroencephalogram (EEG), and
* receiving transcranial magnetic stimulation (TMS). Visits 2 and 3 will take approximately 3 hours each and will be separated from each other by at least 3 weeks.