Hypofractionated Radiation Therapy for Merkel Cell Carcinoma

Participation Deadline: 09/01/2028
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Description

* To estimate the 2-year local control rate for adjuvant hypofractionated RT to the primary tumor bed.
* To estimate the 2-year nodal control rate for adjuvant hypofractionated RT to the primary draining nodal basin.

Secondary Objectives

* To determine MCC disease outcomes including:time to non-nodal locoregional recurrence, time to nodal recurrence, time to distant mestasis, disease-free-survival and disease-specific survival for patients receiving hypofractionated adjuvant RT.
* To assess acute and late RT associated toxicity within or neighboring the radiated field.